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PCSK9i drugs are alternatives to statins

DEAR DR ROACH: In a recent column, you wrote about reducing cholesterol with the help of statins along with a PCSK9i, such as Repatha or Praluent. My question is: Are these PCSK9is at all beneficial if one cannot take statins? –– D.C.S. ANSWER: Yes, PCSK9 inhibitors are very effective at lowering cholesterol and reducing the risk of heart attack in high-risk people. Because these drugs are given by injection and are quite expensive, they are not usually the first-line treatments. We have decades of experience using statins, so they remain the first choice for most. However, if a ...

Fault-finding friends

Dear Annie: My spouse and I have longtime friends who visit from out of town several times a year. We’ve kept up this tradition for many years, and in return we also visit them. At first, these visits were enjoyable, but lately they’ve become a source of stress. It began with small comments –– they said the guest bed wasn’t comfortable and our towels smelled odd. Wanting to be gracious, my wife bought brand-new towels before their next visit. But then they complained the new ones were too small. On their following trip, the criticism shifted to our dishes and silverware, ...

Eating refrozen meats

Dear Heloise: I read a letter in your column about eating chicken that was stored unwrapped. At the end of your answer, you said never to refreeze meats, fowl or seafood after they’ve been thawed out. I had a butcher tell me years ago that it was OK to do, and I’ve been doing it since then without a problem. –– Sharon G., in Tucson, Arizona Sharon, refreezing meat, poultry and seafood may not kill you, but there will be some changes. If you have thawed out the meat in the refrigerator, it’s usually safe enough to consume. But the changes in the product will result in meat ...

Horoscope

ARIES (March 21-April 19). In the animistic belief of shamanic tradition, everything in nature is alive and has spirit, including stones, oceans and mountains. You’ll feel as though you’re in communication with all of it. “There is a voice that doesn’t use words. Listen.” -- Rumi TAURUS (April 20-May 20). Charm relies on context. When someone admired acts silly, it feels delightful. When someone overlooked does the same, it risks dismissal. Avoid playing to type, as the performance will fade into the background. Keep ‘em guessing. GEMINI (May 21-June 21). Instead of ...

Today in History

Today is Monday, Sept. 29, the 272nd day of 2025. There are 93 days left in the year. Today in history: On Sept. 29, 1954, Willie Mays of the New York Giants made a running, over-the-shoulder catch of a ball hit by Vic Wirtz of the Cleveland Indians in Game 1 of the 1954 World Series; “The Catch” would become one of the most famous plays in baseball history. Also on this date: In 1789, Congress officially established a regular army under the U.S. Constitution. In 1938, British, French, German and Italian leaders concluded the Munich Agreement, which was aimed at appeasing ...

Officers recall courage of detectives killed in ambush

LEWISTOWN — An Indian Valley High School graduate, who was among three Pennsylvania detectives shot to death last week, was remembered at a funeral Thursday as an exemplary officer and devoted family man. The service for Northern York County Regional Police detectives Cody Michael Becker, Mark Edward Baker and Isaiah Emenheiser was held more than a week after they were ambushed by a man who had been inside the home of a woman he was accused of stalking. Baker, 53, who lived in Dover at the time of the shooting, graduated from Indian Valley High School in 1990. His obituary states ...