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Daily pill may work as well as Wegovy shots to treat obesity

2 min read

The Associated Press

What if treating obesity could be as easy as popping an effective pill?

That's a notion that has long fueled hope for many of the more than 40% of Americans who are considered obese -- and fueled criticism by those who advocate for wider weight acceptance. Soon, it may be a reality.

High-dose oral versions of the medication in the weight-loss drug Wegovy may work as well as the popular injections when it comes to paring pounds and improving health, according to final results of two studies released Sunday night. The potent tablets also appear to work for people with diabetes, who notoriously struggle to lose weight.

Drugmaker Novo Nordisk plans to ask the U.S. Food and Drug Administration to approve the pills later this year.

"If you ask people a random question, 'Would you rather take a pill or an injection?' People overwhelmingly prefer a pill," said Dr. Daniel Bessesen, chief of endocrinology at Denver Health, who treats patients with obesity but was not involved in the new research.

That's assuming, Bessesen said, that both ways to take the medications are equally effective, available and affordable. "Those are the most important factors for people," he said.

There have been other weight-loss pills on the market, but none that achieve the substantial reductions seen with injected drugs like Wegovy. People with obesity will be "thrilled" to have an oral option that's as effective, said Dr. Katherine Saunders, clinical professor of medicine at Weill Cornell Health and co-founder of Intellihealth, a company that focuses on obesity treatment.

Starting at /week.